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However, the incidences of headache, flushing, dyspepsia and myalgia were significantly greater in the tadalafil group than in the placebo group P 0,0. Currently two more PDE-5 inhibitors, tadalafil and vardenafil, are under study. Not everyone has accepted this yet, says Beverly Whipple, a neurophysiologist who co-wrote a cost low tadalafil book about the G spot in the 1980s.

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Even so, the small size of the area should make a G-spot orgasm unlikely.

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